Co-occurrence of Chiari malformations and sickle cell disease-a diagnostic dilemma: a report of 4 cases and review of literature

Autor: A. B. Scott-Emuakpor, Roshni Kulkarni, Renuka Gera, Elna Saah, Satheesh Chonat
Rok vydání: 2011
Předmět:
Zdroj: Journal of pediatric hematology/oncology. 33(8)
ISSN: 1536-3678
Popis: The co-occurrence of sickle cell disease (SCD) and Chiari malformation (CM) poses clinical and diagnostic challenge since symptoms of both conditions may overlap. Although SCD and CM do not have a causal relationship, the overlapping neurologic symptoms may pose a diagnostic dilemma. To the best of our knowledge, the clinical manifestations and long-term consequence of CM in children with SCD has hitherto not been reported in the literature. We describe clinical manifestations of co-occurrence of SCD and CM in a case series of 4 African American children.
Databáze: OpenAIRE