Dosimetric comparison of inverse optimisation methods versus forward optimisation in HDR brachytherapy of breast, cervical and prostate cancer
| Autor: | Georgina Fröhlich, Júlia Vízkeleti, Péter Ágoston, Tibor Major, Csaba Polgár, Gyula Geszti |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Zervix-Brachytherapie
Male medicine.medical_treatment Brachytherapy Cervical brachytherapy Planning target volume IPSA inverse planning simulated annealing Rectum Uterine Cervical Neoplasms Breast Neoplasms 030218 nuclear medicine & medical imaging 03 medical and health sciences Prostate cancer 0302 clinical medicine Prostate HIPO hybrid inverse planning optimisation Medicine Humans Radiology Nuclear Medicine and imaging Radiometry Inverse optimisation algorythms business.industry Prostata-Brachytherapie Radiotherapy Planning Computer-Assisted Prostatic Neoplasms Radiotherapy Dosage HIPO model medicine.disease Mamma-Brachytherapie Radiation therapy medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Breast brachytherapy Original Article Prostate brachytherapy Inverse Optimierung algorithmus Female business Nuclear medicine Algorithms Radiotherapy Image-Guided |
| Zdroj: | Strahlentherapie Und Onkologie |
| ISSN: | 1439-099X 0179-7158 |
| Popis: | Objective Dosimetric comparison of HIPO (hybrid inverse planning optimisation) and IPSA (inverse planning simulated annealing) inverse and forward optimisation (FO) methods in brachytherapy (BT) of breast, cervical and prostate cancer. Methods At our institute 38 breast, 47 cervical and 50 prostate cancer patients treated with image-guided interstitial high-dose-rate BT were selected. Treatment plans were created using HIPO and IPSA inverse optimisation methods as well as FO. The dose–volume parameters of different treatment plans were compared with Friedman ANOVA and the LSD post-hoc test. Results IPSA creates less dose coverage to the target volume than HIPO or FO: V100 was 91.7%, 91% and 91.9% for HIPO, IPSA and FO plans (p = 0.1784) in breast BT; 90.4%, 89.2% and 91% (p = 0.0045) in cervical BT; and 97.1%, 96.2% and 97.7% (p = 0.0005) in prostate BT, respectively. HIPO results in more conformal plans: COIN was 0.72, 0.71 and 0.69 (p = 0.0306) in breast BT; 0.6, 0.47 and 0.58 (p |
| Databáze: | OpenAIRE |
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