Transition metal-catalyzed regio- and stereoselective aminobromination of olefins with TsNH2 and NBS as nitrogen and bromine sources

Autor:	Vinay V. Thakur, Arumugam Sudalai, Siva Kumar Talluri
Rok vydání:	2003
Předmět:	Bromine Organic Chemistry chemistry.chemical_element General Medicine Biochemistry Nitrogen Catalysis chemistry Transition metal Polymer chemistry Organic chemistry Stereoselectivity Physical and Theoretical Chemistry Vicinal
Zdroj:	Organic letters. 5(6)
ISSN:	1523-7060
Popis:	[reaction: see text] A new synthetic procedure for aminohalogenation of olefins has been developed for the preparation of vicinal haloamine derivatives in high yields by using Cu, Mn, or V catalysts with p-toluenesulfonamide (TsNH(2)) and N-bromosuccinimide (NBS) as nitrogen and bromine sources, respectively. Unprecedented regio- and stereoselectivity (anti:syn99:1) toward the aminohalogenation process is shown for olefinic substrates as well as transition metal catalysts.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fbad1fb7e1c06f29bdca10bbeb8599 https://pubmed.ncbi.nlm.nih.gov/12633091 Zobrazit plný text záznamu