Clinical utility of skin cancer and melanoma risk scores for population screening: TRoPICS study
| Autor: | K Fry, Rachel E. Neale, B Yau, S Thomas, S. Brown, Monika Janda, Catherine M. Olsen, K Lun, Adèle C. Green, Jenna E. Rayner, H Jenkins, J Parbery, L Spelman, G. Wagner, A Shetty, Kiarash Khosrotehrani, Hans Peter Soyer, L. A. von Schuckmann, David C. Whiteman |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Skin Neoplasms Risk management tools Dermatology Sensitivity and Specificity 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Environmental risk Risk Factors Commentaries Medicine Humans Basal cell carcinoma Melanoma Early Detection of Cancer Framingham Risk Score business.industry medicine.disease Infectious Diseases Carcinoma Basal Cell 030220 oncology & carcinogenesis Commentary Community setting Population screening Skin cancer business |
| Zdroj: | Journal of the European Academy of Dermatology and Venereology |
| ISSN: | 1468-3083 |
| Popis: | Background: Screening for skin cancer can be cost‐effective if focused on high‐risk groups. Risk prediction tools have been developed for keratinocyte cancers and melanoma to optimize advice and management. However, few have been validated in a clinical setting over the past few years.Objectives: To assess the clinical utility of risk assessment tools to identify individuals with prevalent skin cancers in a volunteer‐based screening clinic.Methods: Participants were adults presenting for a skin check at a volunteer‐based skin cancer screening facility. We used previously published tools, based on questionnaire responses, to predict melanoma and keratinocyte cancers [KCs; basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)] and classified each participant into one of five risk categories. Participants subsequently underwent a full skin examination by a dermatologist. All suspicious lesions were biopsied, and all cancers were histopathologically confirmed.Results: Of 789 people who presented to the clinic, 507 (64%) consented to the study. Twenty‐two BCCs, 19 SCCs and eight melanomas were diagnosed. The proportion of keratinocyte cancers diagnosed increased according to risk category from |
| Databáze: | OpenAIRE |
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