Nanoparticles-Mediated CRISPR/Cas Gene Editing Delivery System

Autor:	Phei Er Saw, Guo‐hui Cui, Xiaoding Xu
Rok vydání:	2022
Předmět:	Pharmacology Gene Editing Organic Chemistry Drug Discovery Molecular Medicine Nanoparticles Genetic Therapy General Pharmacology Toxicology and Pharmaceutics CRISPR-Cas Systems Biochemistry
Zdroj:	ChemMedChem. 17(9)
ISSN:	1860-7187
Popis:	CRISPR/Cas system has become one of the most powerful techologies in biomedical research, and has showed great potentials in the gene related diseases. However, efficient delivery systems of CRISPR/Cas to target cells remains challenging. In recent years, nanoparticles have showned great potentials for the delivery of CRISPR/Cas systems. This paper mainly approaches the development and new strategies of CRISPR/Cas delivery systems, as well as their application in the clinical diseases. By summarizing the CRISPR/Cas systems delivery, new strategies are expected for the gene therapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f18295b7ba9682a995fefeef165cc4 https://pubmed.ncbi.nlm.nih.gov/35261159 Zobrazit plný text záznamu Plný text