Estimation ofin vivo proton intrinsic and cross-relaxation rates in human brain
| Autor: | Jyh‐Wen Chai, Clayton Chen, Hong N. Yeung, Joen Hor Chen, San-Kan Lee |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Proton Physics::Medical Physics Nuclear magnetic resonance Body Water In vivo medicine Humans Radiology Nuclear Medicine and imaging Magnetization transfer Saturation (magnetic) Cerebrospinal Fluid medicine.diagnostic_test Chemistry Electron Spin Resonance Spectroscopy Brain Magnetic resonance imaging Human brain Middle Aged Image Enhancement Magnetic Resonance Imaging Cross relaxation medicine.anatomical_structure Principal component analysis Protons Algorithms |
| Zdroj: | Magnetic Resonance in Medicine. 36:147-152 |
| ISSN: | 1522-2594 0740-3194 |
| DOI: | 10.1002/mrm.1910360123 |
| Popis: | By using on-resonance binomial pulse saturation of the immobile component in tissues and by monitoring the time development of the longitudinal decay of the free water magnetization, it has been shown that it is possible to estimate physical model parameters not directly measurable by conventional methods. Since pulsed saturation is easy and safe to implement in a clinical MRI machine, it should be possible to estimate these parameters in vivo by the same means. In this article, we report the results of such estimates of the parameters of the principal components (gray and white matter) in brains of two normal volunteers. |
| Databáze: | OpenAIRE |
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