Antibacterial activity of eight Brazilian annonaceae plants
| Autor: | Maria Amélia D. Boaventura, Luiz G. F. e Silva, Cássia R Pereira, Jacqueline A. Takahashi, Lúcia Pinheiro Santos Pimenta |
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| Rok vydání: | 2005 |
| Předmět: |
biology
Traditional medicine Plant Extracts Organic Chemistry Thin layer Annona ambotay Annonaceae Plant Science Microbial Sensitivity Tests biology.organism_classification Biochemistry Analytical Chemistry Anti-Bacterial Agents Phytochemical Species Specificity Botany Xylopia frutescens Chromatography Thin Layer Annona Antibacterial activity Xylopia |
| Zdroj: | Natural product research. 20(1) |
| ISSN: | 1478-6419 |
| Popis: | Sixteen extracts, obtained from eight Brazilian plants of Annonaceae family, were screened for their antibacterial activity: Xylopia frutescens, X. aromatica, X. amazonica, X. benthamii, Annona ambotay, A. crassiflora, A. muricata and A. cherimolia. Amongst the investigated extracts, six showed antibacterial activity against at least one of the tested organisms at the concentration of 100 microg/mL. The most active extracts were those prepared from X. frutescens, X. amazonica, and A. ambotay. A phytochemical screening showed the presence of anonaceus acetogenins in some active extracts. Eleven diterpenoids were also tested for comparison purposes. Six were natural products, previously isolated from Xylopia sp. (kaurenoic, frutoic, xylopic, 15beta-hydroxy-kaurenoic and trachylobanic acids plus kaurenol) and five were derivatives of such compounds, obtained by esterification or reduction reactions. Trachylobanic acid showed antibacterial activity against B. subtilis and S. aureus. |
| Databáze: | OpenAIRE |
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