Clinical symptoms associated with laboratory findings and placental histopathology in full-term, non-infected neonates born to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive mothers
| Autor: | Ariadne Malamitsi-Puchner, Vassiliki Papaevangelou, Anastasia E. Konstantinidou, Kleopatra Paparizou, Nikolaos Siafakas, Garyfallia Syridou, Despina D. Briana |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Diarrhea
Coronavirus disease 2019 (COVID-19) Sucking Reflex Placenta Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Ischemia Physiology Proinflammatory cytokine Pregnancy medicine Humans Pregnancy Complications Infectious Full Term Asphyxia SARS-CoV-2 business.industry Infant Newborn Parturition COVID-19 Obstetrics and Gynecology medicine.disease Infectious Disease Transmission Vertical Pediatrics Perinatology and Child Health Female medicine.symptom business |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 35:8706-8709 |
| ISSN: | 1476-4954 1476-7058 |
| DOI: | 10.1080/14767058.2021.1998894 |
| Popis: | This study comprehensively examines clinical symptoms, laboratory findings, and placental pathology in 40 cases of singleton full-term SARS-CoV-2 negative neonates. Their mothers, previously healthy, with uncomplicated pregnancies, were infected peripartum and presented COVID-19 symptoms of various severity. Neonates had predominately diarrhea, the yet unreported absent sucking reflex, elevated COVID-19 inflammatory and ischemia/asphyxia markers as serum ferritin, interleukin-6 and cardiac troponin-T, while placentas demonstrated mild vascular and/or inflammatory lesions. We hypothesize that the above placental lesions may be associated with transient perinatal hypoxia resulting in absent sucking reflex, as well as with inflammatory cytokines transfer causing diarrhea. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|