Impaired Antiatherogenic Function of High-Density Lipoproteins in the Presence of Various Risk Factors for Coronary Heart Disease
| Autor: | Perova Nv, T. V. Kamyshova, A. P. Serdyuk, V. A. Metel’skaya, I. N. Ozerova |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Carcinoma Hepatocellular Urban Population Phospholipid Blood lipids Blood Pressure Coronary Disease Hyperlipidemias General Biochemistry Genetics and Molecular Biology Body Mass Index chemistry.chemical_compound Blood serum Risk Factors Internal medicine Hyperlipidemia Tumor Cells Cultured medicine Humans Cholesterol business.industry Body Weight Cholesterol HDL Liver Neoplasms Reverse cholesterol transport General Medicine Middle Aged medicine.disease Endocrinology chemistry Cardiology lipids (amino acids peptides and proteins) business Function (biology) Lipoprotein |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 139:290-292 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-005-0274-6 |
| Popis: | We studied acception of cholesterol from Fu5AH hepatoma cells by blood serum from subjects with normal level of high-density lipoprotein cholesterol and hyperlipidemia (alone or in combination with other risk factors for coronary heart disease). Cholesterol-binding activity of high-density lipoproteins decreased in subjects with hyperlipidemia alone or in combination with excess body weight and/or arterial hypertension. Impairment of high-density lipoprotein activity was associated with changes in their phospholipid composition. |
| Databáze: | OpenAIRE |
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