Chemical Reporters for Exploring Microbiology and Microbiota Mechanisms
| Autor: | Zhenrun J. Zhang, Howard C. Hang, Yen Chih Wang, Xinglin Yang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
010405 organic chemistry
Microbiota Metabolite Organic Chemistry Proteins Computational biology Biology Gram-Positive Bacteria 010402 general chemistry 01 natural sciences Biochemistry Article 0104 chemical sciences chemistry.chemical_compound chemistry Gram-Negative Bacteria Humans Molecular Medicine Bioorthogonal chemistry Molecular Biology |
| Zdroj: | Chembiochem |
| ISSN: | 1439-7633 1439-4227 |
| DOI: | 10.1002/cbic.201900535 |
| Popis: | The advances made in bioorthogonal chemistry and the development of chemical reporters have afforded new strategies to explore the targets and functions of specific metabolites in biology. These metabolite chemical reporters have been applied to diverse classes of bacteria including Gram-negative, Gram-positive, mycobacteria, and more complex microbiota communities. Herein we summarize the development and application of metabolite chemical reporters to study fundamental pathways in bacteria as well as microbiota mechanisms in health and disease. |
| Databáze: | OpenAIRE |
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