Case Report: Microcephaly in Twins due to the Zika Virus
| Autor: | Sheila Jaqueline Gomes dos Santos Oliveira, Cliomar Alves dos Santos, Paulo Ricardo Saquete Martins-Filho, Victor Santana Santos, Dorothy Ribeiro Resende Lima, Ricardo Queiroz Gurgel |
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| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty Microcephaly Adolescent Zika virus 03 medical and health sciences 0302 clinical medicine Pregnancy Virology Diseases in Twins ZikV Infection medicine Humans 030212 general & internal medicine Pregnancy Complications Infectious Twin Pregnancy Genetics Fetus biology Zika Virus Infection Infant Newborn Articles medicine.disease biology.organism_classification Infectious Diseases Etiology Exotropia Female Parasitology 030217 neurology & neurosurgery |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 97:151-154 |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.16-1021 |
| Popis: | Recent studies have demonstrated an association between congenital Zika virus (ZIKV) infection and microcephaly; however, to date, there have been no reports on the consequences of ZIKV infection on fetuses in twin pregnancies. Herein, we reported on the first case of a monochorionic diamniotic (MCDA) twin pregnancy having ZIKV-related microcephaly. Our findings suggested that, in an MCDA twin pregnancy, the ZIKV may cause infection in both fetuses, resulting in severe abnormalities in the central nervous system due to neural cell destruction and the disruption of the normal development processes of the brain. This case report and other similar twin cases may help to understand the pathogenesis and to confirm the etiology of ZIKV as a teratogenic microorganism. |
| Databáze: | OpenAIRE |
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