| Autor: |
Kun‐Hua He, Lu‐Qiong Xu, Ying‐Feng Hu, Yin‐Xia Xu, Yu Zhao, Jing‐Yan Bao, Bu‐Qiang Wang |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Health Science Reports. 5 |
| ISSN: |
2398-8835 |
| DOI: |
10.1002/hsr2.891 |
| Popis: |
There are few analyses of the 15 red blood group system antigen coding genes found in the Yunnan Yi nationality. This has caused many poteintial dangers relating to clinical blood transfusion. In this report, the coding genes and distribution of 15 blood group antigens system in the Yi nationality were tested and compared with those of Han nationality and other ethnic minorities.The samples came from the healthy subjects in the first people's Hospital of Qujing, Yunnan Province. Two hundred and three Yunnan Yi and 197 Han nationality individuals were included. Thirty-three blood group antigens with a low frequency from the 15 blood group systems of Yunnan Yi blood donors were genotyped and analyzed by PCR-SSP. Sanger sequencing was used to detect A4GALT from the Yunnan Yi nationality. TheThe ABO blood group examination results for the Yi nationality and the local Han nationality in Qujing City, Yunnan Province, showed the majority were type A and type O, while the least prevalent was type AB. RhD+ accounts for more than 98% of the Yi and Han populations. There was a significant difference in ABO blood group antigen distribution between these two nationalities (Yunnan Yi nationality has a unique genetic background. There are some significantly different distributions of blood group system genes with a low frequency in different regions and groups in China. Multiple mutations in the A4GALT gene of the P1PK blood group system may be related to their environment and ethnic evolution. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Plný text