Long-term recurrences of jaw osteoradionecrosis after apparent healing with the PENTOCLO protocol
| Autor: | François Bidault, A. Dinnoo, Antoine Moya-Plana, M. Elmaalouf, François Janot, N. Benmoussa, N. Lassau, A. Ruffier |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Osteoradionecrosis business.industry Late complication Tocopherols 030206 dentistry Head and neck irradiation medicine.disease Surgery Drug Combinations 03 medical and health sciences 0302 clinical medicine Otorhinolaryngology Head and Neck Neoplasms medicine Humans Clodronic Acid Neoplasm Recurrence Local Pentoxifylline Oral Surgery 030223 otorhinolaryngology business |
| Zdroj: | Journal of Stomatology, Oral and Maxillofacial Surgery. 121:286-287 |
| ISSN: | 2468-7855 |
| DOI: | 10.1016/j.jormas.2019.06.007 |
| Popis: | Osteoradionecrosis of the jaws (ORNJ) is a late complication of head and neck irradiation estimated at around 3% of irradiated patients. The PENTO protocol (Pentoxyfilline and Tocopherol), with the eventual adjunction of Clodronate (PENTOCLO), showed interesting results even in advanced ORNJ. The current literature does not describe the long-term outcomes and particularly after the completion of the protocol. The PENTO or PENTOCLO protocol should be prescribed as a life-long treatment or the outcome should be monitored at least as long as the duration of the protocol after its end. |
| Databáze: | OpenAIRE |
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