Heparin-surface-modified intraocular lenses in pediatric cataract surgery: prospective randomized study
| Autor: | Sreelakshmi Reddy, Satish Gupta, Murali K Aasuri, Madhukar K. Reddy, Surendra Basti, Thomas Naduvilath, Padmaja Preetam |
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| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Visual acuity genetic structures Adolescent medicine.medical_treatment Eye disease Visual Acuity Vitrectomy Intraocular lens law.invention Randomized controlled trial Coated Materials Biocompatible Double-Blind Method Lens Implantation Intraocular law Ophthalmology medicine Humans Polymethyl Methacrylate Prospective Studies Posterior Capsulotomy Prospective cohort study Child Capsulorhexis Lenses Intraocular business.industry Heparin equipment and supplies medicine.disease eye diseases Sensory Systems Surgery Treatment Outcome Child Preschool Female sense organs medicine.symptom business Follow-Up Studies |
| Zdroj: | Journal of cataract and refractive surgery. 25(6) |
| ISSN: | 0886-3350 |
| Popis: | To evaluate the performance of heparin-surface-modified (HSM) intraocular lenses (IOLs) in pediatric eyes after cataract surgery.L.V. Prasad Eye Institute, Hyderabad, India.This prospective, randomized, double-masked, controlled clinical trial comprised 90 children aged 2 to 14 years with cataract. The patients were consecutively randomized to receive an HSM (Group 1) or an unmodified (Group 2) poly(methyl methacrylate) (PMMA) IOL. Extracapsular cataract extraction (ECCE) with IOL implantation was performed in children 8 years and older and ECCE with primary posterior capsulotomy, anterior vitrectomy, and IOL implantation in children younger than 8 years. Outcome parameters were inflammatory cell deposits on the IOL surface, posterior synechias, and anterior chamber reaction.Follow-up data were available for 73, 70, 60, and 68 patients at 1 week, 1 month, 3 months, and 6 months, respectively. Significantly fewer cell deposits were noted in Group 1 at 1, 3, and 6 months (P.001). Synechia formation and anterior chamber reaction were comparable in the 2 groups.The lower incidence of inflammatory cell deposit formation in eyes with HSM PMMA IOLs indicates that these IOLs have greater bicompatibility than unmodified IOLs in pediatric cataract surgery. |
| Databáze: | OpenAIRE |
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