Positive pleural cytology is an indicator for visceral pleural invasion in metastatic pleural effusions
| Autor: | Dan Adler, Stavros Anevlavis, Elise Kaspi, Philippe Astoul, Georgia Karpathiou, Elisa Roca, Sophie Laroumagne, Hervé Dutau, Marios Froudarakis, Jérôme Pierre Olivier Plojoux |
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| Přispěvatelé: | Democritus University of Thrace (DUTH), Hôpitaux Universitaires de Genève (HUG), Laboratoire de Biologie Cellulaire [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Marseille medical genetics - Centre de génétique médicale de Marseille (MMG), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Nord [CHU - APHM], University Hospital of Ioannina, Physiopathologie de l'Endothelium, Vascular research center of Marseille (VRCM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Division d'oncologie thoracique, Département des maladies pulmonaires, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille (APHM)-Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre recherche en CardioVasculaire et Nutrition (C2VN) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Mesothelioma Lung Neoplasms Pleural effusion medicine.medical_treatment Thoracentesis Gastroenterology Malignant/epidemiology/pathology/surgery 0302 clinical medicine Cytology Immunology and Allergy Medicine Malignant pleural effusion 10. No inequality Genetics (clinical) ddc:616 Survival Rate/trends Univariate analysis medicine.diagnostic_test Greece Incidence Pleural Neoplasms/pathology Exudates and Transudates Middle Aged respiratory system Pleura/pathology 3. Good health Bloody Survival Rate Exudates and Transudates/cytology 030220 oncology & carcinogenesis Pleura Female Pulmonary and Respiratory Medicine medicine.medical_specialty Pleural Neoplasms cytology malignant pleural effusion thoracoscopy Greece/epidemiology Lung Neoplasms/diagnosis/secondary Mesothelioma/diagnosis/secondary 03 medical and health sciences Internal medicine Thoracoscopy Humans Aged Retrospective Studies business.industry Mesothelioma Malignant medicine.disease Thoracentesis/methods Pleural Effusion Malignant respiratory tract diseases Pleural Effusion 030228 respiratory system [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics business |
| Zdroj: | CLINICAL RESPIRATORY JOURNAL CLINICAL RESPIRATORY JOURNAL, 2018, 12 (3), pp.1011-1016. ⟨10.1111/crj.12619⟩ The Clinical Respiratory Journal, Vol. 12, No 3 (2018) pp. 1011-1016 |
| ISSN: | 1752-6981 |
| DOI: | 10.1111/crj.12619⟩ |
| Popis: | International audience; IntroductionIn case of undiagnosed pleural effusions, it is necessary to conduct thoracentesis with pleural fluid (PF) cytology. Yet, sensitivity of PF cytology is widely variable as a result of sample size, experience, and preparation method. ObjectivesThe aim of this study was to assess whether pleural fluid (PF) cytology is correlated to visceral or parietal pleural invasion as assessed by thoracoscopy in metastatic pleural effusions. MethodsAll records of patients with pleural effusion were reviewed. The inclusion criteria were as follows: PF cytology, reported appearance of macroscopic pleural invasion during thoracoscopy and malignant diagnosis. Patients with mesothelioma were excluded. Finally, 287 patients who met all criteria were selected. According to the thoracoscopy findings, the extent of the disease on the pleura was analyzed in relation to the PF cytology. ResultsIn this study, 160 patients (55.7%) had a positive PF cytology (Group A) while 127 (44.3%) recorded negative PF cytology (Group B). From Group A, patients with visceral pleural invasion were 120 (75%) while only 49 patients (38.5%) were found from Group B and the difference was statistically significant (P |
| Databáze: | OpenAIRE |
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