The case report of Mycobacterium arupense wound infection in diabetes mellitus patients; the first report and literature review
| Autor: | Melika Hasani, Sepehr Navid, Arezoo Mirzaei, Masoud Youssefi, Kiarash Ghazvini, Masoud Keikha, Bahar Sadegh-Ehdaei, Mehdi Shabani |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Mycobacterium arupense
medicine.medical_specialty Rifabutin biology business.industry Case Report biology.organism_classification medicine.disease Pathogenicity Wound infection Lesion Clarithromycin Internal medicine Diabetes mellitus diabetes mellitus medicine wound infection General Materials Science medicine.symptom 16S rRNA business Ethambutol medicine.drug |
| Zdroj: | Access Microbiology |
| ISSN: | 2516-8290 |
| Popis: | Mycobacterium arupense is among the opportunist pathogens of atypical mycobacteria emergence (atypical mycobacteria) that is one of the isolated and reported environmental and clinical specimens. Numerous cases of osteo-articular infections of this bacterium are reported nowadays, while the pulmonary infection is rare. We identified Mycobacterium arupense in non-healing wound infection of an elderly woman with history of diabetes mellitus. She has negative tests for HIV, HBV and HCV, but was positive for HTLV-1. The patient was referred according to mild-fever, non-healing, destructive, and swelled lesion on her left foot. The mycobacterial wounds infection was suspected due to her non-conclusive previous treatment. The pathology, acid-fast staining, conventional and 16S rRNA sequencing confirmed the micro-organism to be M. arupense . Finally, the patient recovered following two-week consumption of clarithromycin, ethambutol and rifabutin. The results of this study provide evidence on the potential pathogenicity, clinical outcomes and treatment of infections caused by this bacterium. |
| Databáze: | OpenAIRE |
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