A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings
| Autor: | Katsuyoshi Tamaki, Mari Urata, Nao Kohno, Ichiro Shimizu, Nobuya Sano, Hiroshi Fukuno, Susumu Ito |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Pathology medicine.medical_specialty Carcinoma Hepatocellular Case Report Metastasis Lumbar Spinal cord compression medicine Paralysis Carcinoma Humans Aged Spinal Neoplasms medicine.diagnostic_test business.industry Liver Neoplasms Gastroenterology Magnetic resonance imaging General Medicine medicine.disease Magnetic Resonance Imaging Hepatocellular carcinoma Disease Progression medicine.symptom Paraplegia business |
| Zdroj: | World Journal of Gastroenterology. 13:2758 |
| ISSN: | 1007-9327 |
| DOI: | 10.3748/wjg.v13.i19.2758 |
| Popis: | Although spinal tumors are uncommon, they may reduce survival or cause serious functional disorders in the extremities. Metastatic spinal tumors from malignant tumors can induce symptoms of spinal cord compression, such as paraplegia, quadriplegia, and vesicorectal disturbance, which are aggravated with progression of the diseases and time. We report a patient with hepatocellular carcinoma (HCC) who was suspected of having spinal lesions based on neurological findings, and a metastatic spinal tumor was found by imaging examination. Assuming that metastasis had occurred at the time lumbar pain developed, the patient reached the level of gait disturbance within only 4 mo, showing a rapid advancement of symptoms. If early diagnosis had been possible, treatment could be performed before acute myelopathy progressed to complete paralysis. We speculate that the terminal stage of HCC is not only liver failure associated with intrahepatic lesions but also metastasis to other regions, treatment for individual pathologies therefore, will be needed, which constitutes an important issue. |
| Databáze: | OpenAIRE |
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