Risk Factors for Varicose Disease Before and During Pregnancy
| Autor: | Moreno Dindelli, Fabio Parazzini, Aldo Basellini, Emanuela Rabaiotti, Giuseppe Corsi, Augusto Ferrari |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Pregnancy High-Risk Pregnancy Complications Cardiovascular 030204 cardiovascular system & hematology Overweight Varicose Veins 03 medical and health sciences 0302 clinical medicine Pregnancy Risk Factors Epidemiology medicine Humans 030212 general & internal medicine Risk factor Family history Vascular disease business.industry Obstetrics Body Weight Age Factors Middle Aged medicine.disease Surgery Parity Relative risk Gestation Female medicine.symptom Cardiology and Cardiovascular Medicine business Maternal Age |
| Zdroj: | Angiology. 44:361-367 |
| ISSN: | 1940-1574 0003-3197 |
| DOI: | 10.1177/000331979304400504 |
| Popis: | Risk factors for varicose disease before and during pregnancy have been analyzed by use of data from a survey on venous disease in pregnancy conducted in 611 women (mean age thirty years, range fifteen to forty-seven) who consecutively delivered at the Obstetric-Gynecologic Clinic "L. Mangiagalli" of Milan between January and April, 1989. In total, 137 women (22%) reported varicose disease before the index pregnancy. The relative risk (RR) of varicose disease before the index pregnancy increased with age, being, as compared with women aged twenty-nine years or less, 1.6 in those aged thirty to thirty-four and 4.1 in those aged thirty-five years or more (χ21 trend 29.28, p < 0.001). Compared with nulliparae, women reporting a full-term pregnancy before the index pregnancy had an RR of venous disease of 1.2, and the risk increased to 3.8 in women reporting two or more births (χ21 trend 25.28, p < 0.001). A family history of varicose disease was associated with an RR of venous disease of 6.2 (95% confidence interval, CI, from 4.1 to 9.6). No relationship emerged between varicose disease and overweight. Of the 474 women who did not report venous disease before the index pregnancy, 132 (28%) developed venous disease during the index pregnancy. The risk of developing venous disease in pregnancy increased with age, being, as compared with women aged twenty-four years or less, 4.0 in those aged thirty-five years or more, and the trend in risk was statistically significant (χ2 1 trend 16.25, p < 0.001). To be secondiparae or more was associated with an increased risk of developing venous disease in pregnancy. Compared with primiparae, the estimated RR was 2.0 (95% CI 1.3 to 2.9) in women reported to have given birth to one child or more. Women who developed venous disease in pregnancy reported more frequently a family history of varicose disease than those who did not; the RR estimate was 5.8, (95% CI from 3.8 to 8.9). |
| Databáze: | OpenAIRE |
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