Techniques: Bioprospecting historical herbal texts by hunting for new leads in old tomes
| Autor: | Brent A. Bauer, Timothy J. Motley, Eric J. Buenz, John M. Riddle, David J. Schnepple, Peter L. Elkin |
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| Rok vydání: | 2004 |
| Předmět: |
Herbal Medicine
Ethnobotany Toxicology History 18th Century History 17th Century Resource (project management) Medicine Humans Traditional knowledge History Ancient History 15th Century Pharmacology Bioprospecting Plants Medicinal Traditional medicine business.industry Plant Extracts Historical Article Manuscripts Medical as Topic History 19th Century Data science History Medieval History 16th Century Identification (biology) Medicine Traditional business Phytotherapy |
| Zdroj: | Trends in pharmacological sciences. 25(9) |
| ISSN: | 0165-6147 |
| Popis: | Ethnobotany has led to the identification of novel pharmacological agents but many challenges to using ethnobotany as a research tool remain. In particular, the loss of traditional knowledge together with the advent of high-throughput screening has made ethnobotanical techniques laborious and potentially unnecessary. However, historical herbal texts provide a preexisting resource that documents the traditional uses of various species as medicines. As generational losses of traditional knowledge accrue, these herbal texts become increasingly valuable. The methodology for extracting useful information contained within these resources had been cumbersome and consuming. However, the application of new bioinformatics data-mining systems to herbal texts holds great promise for identifying novel pharmacotherapeutic leads for bioactive compounds. |
| Databáze: | OpenAIRE |
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