In Vitro Antimicrobial Activity of Some Medicinal Plants against Human Pathogenic Bacteria
| Autor: | Raj Kumar Dahal, Sarita Manandhar, Shisir Luitel |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
lcsh:Arctic medicine. Tropical medicine food.ingredient Article Subject lcsh:RC955-962 medicine.disease_cause Microbiology 03 medical and health sciences 0302 clinical medicine food medicine Ageratina adenophora Agar diffusion test Medicinal plants Artemisia vulgaris biology Traditional medicine Oxalis corniculata Pathogenic bacteria General Medicine biology.organism_classification Antimicrobial 030104 developmental biology 030220 oncology & carcinogenesis Parasitology Cinnamomum tamala Research Article |
| Zdroj: | Journal of Tropical Medicine, Vol 2019 (2019) Journal of Tropical Medicine |
| ISSN: | 1687-9694 1687-9686 |
| DOI: | 10.1155/2019/1895340 |
| Popis: | The emergence and spread of antibiotic resistance, as well as the evolution of new strains of disease causing agents, are of great concern to the global health community. Effective treatment of a disease entails the development of new pharmaceuticals or some potential source of novel drugs. Commonly used medicinal plants of our community could be an excellent source of drugs to fight off this problem. This study is focused on exploring the antimicrobial properties of the plants that are commonly being used as traditional medicines. The antimicrobial potential of four different plant extracts was screened against twelve pathogenic microorganisms and two reference bacterial strains. Methanolic extracts of Oxalis corniculata, Artemisia vulgaris, Cinnamomum tamala, and Ageratina adenophora were subjected to a test of their antimicrobial properties by agar well diffusion method. The result indicated that most of the extracts exhibited antimicrobial properties. The highest potential was observed in the extract of O. corniculata against Escherichia coli, Salmonella Typhi, MDR Salmonella Typhi, Klebsiella pneumoniae, and Citrobacter koseri with zone of inhibition (ZOI) of 17 mm, 13 mm, 16 mm, 11 mm, and 12 mm, respectively. Oxalis corniculata also showed the highest MIC against test organisms. The methanolic extract of Artemisia vulgaris, Cinnamomum tamala, and Ageratina adenophora showed efficacy against Staphylococcus aureus. Ageratina adenophora also showed antifungal activity against Rhizopus spp. The experiment confirmed the efficacy of some selected plant extracts as natural antimicrobials and suggested the possibility of employing them in drugs for the treatment of infectious diseases caused by the test organisms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |