Cough following low thoracic hemisection in the cat
| Autor: | Nicole J. Tester, Adele E. Blum, Dena R. Howland, Stephanie C. Jefferson, Melanie J. Rose, Donald C. Bolser, Brian G. Howland |
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| Rok vydání: | 2010 |
| Předmět: |
Time Factors
Electromyography Functional Laterality Thoracic Vertebrae Article Central nervous system disease Developmental Neuroscience medicine Animals Esophagus Respiratory system Spinal cord injury Spinal Cord Injuries Abdominal Muscles Analysis of Variance medicine.diagnostic_test business.industry medicine.disease medicine.anatomical_structure Cough Neurology Anesthesia Thoracic vertebrae Cats Reflex Female Brainstem business |
| Zdroj: | Experimental Neurology. 222:165-170 |
| ISSN: | 0014-4886 |
| DOI: | 10.1016/j.expneurol.2009.12.015 |
| Popis: | A function of the abdominal expiratory muscles is the generation of cough, a critical respiratory defense mechanism that is often disrupted following spinal cord injury. We assessed the effects of a lateral T9/10 hemisection on cough production at 4, 13 and 21 weeks post-injury in cats receiving extensive locomotor training. The magnitudes of esophageal pressure as well as of bilateral rectus abdominis electromyogram activity during cough were not significantly different from pre-injury values at all time points evaluated. The results show that despite considerable interruption of the descending pre-motor drive from the brainstem to the expiratory motoneuron pools, the cough motor system shows a significant function by 4 weeks following incomplete thoracic injury. |
| Databáze: | OpenAIRE |
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