Tea Drinking and Its Association with Active Tuberculosis Incidence among Middle-Aged and Elderly Adults: The Singapore Chinese Health Study
| Autor: | Woon-Puay Koh, Avril Z. Soh, Jian-Min Yuan, Cynthia B.E. Chee, An Pan, Yee-Tang Wang |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Tuberculosis tea Population lcsh:TX341-641 Coffee Article Cohort Studies Mycobacterium tuberculosis 03 medical and health sciences 0302 clinical medicine Asian People Environmental health Epidemiology Humans Medicine 030212 general & internal medicine education Aged Proportional Hazards Models Singapore education.field_of_study Nutrition and Dietetics Traditional medicine biology business.industry Incidence Incidence (epidemiology) Hazard ratio Middle Aged medicine.disease biology.organism_classification 3. Good health 030104 developmental biology tuberculosis Cohort Female epidemiology business lcsh:Nutrition. Foods and food supply Food Science Cohort study |
| Zdroj: | Nutrients, Vol 9, Iss 6, p 544 (2017) Nutrients; Volume 9; Issue 6; Pages: 544 Nutrients |
| ISSN: | 2072-6643 |
| Popis: | Experimental studies showed that tea polyphenols may inhibit growth of Mycobacterium tuberculosis. However, no prospective epidemiologic study has investigated tea drinking and the risk of active tuberculosis. We investigated this association in the Singapore Chinese Health Study, a prospective population-based cohort of 63,257 Chinese aged 45–74 years recruited between 1993 and 1998 in Singapore. Information on habitual drinking of tea (including black and green tea) and coffee was collected via structured questionnaires. Incident cases of active tuberculosis were identified via linkage with the nationwide tuberculosis registry up to 31 December 2014. Cox proportional hazard models were used to estimate the relation of tea and coffee consumption with tuberculosis risk. Over a mean 16.8 years of follow-up, we identified 1249 incident cases of active tuberculosis. Drinking either black or green tea was associated with a dose-dependent reduction in tuberculosis risk. Compared to non-drinkers, the hazard ratio (HR) (95% confidence interval (CI)) was 1.01 (0.85–1.21) in monthly tea drinkers, 0.84 (0.73–0.98) in weekly drinkers, and 0.82 (0.71–0.96) in daily drinkers (p for trend = 0.003). Coffee or caffeine intake was not significantly associated with tuberculosis risk. In conclusion, regular tea drinking was associated with a reduced risk of active tuberculosis. |
| Databáze: | OpenAIRE |
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