Liver Transplantation at the Cuban Center for Medical and Surgical Research
| Autor: | F. Gómez, S.A. Collera, P.P. Benı́tez, L González, R. Ysla, J. Castillo, L. Ramos, A. Fernández, Oscar A López, M. Samada, José Daniel Díaz Díaz, F.D. Ávalo, Julio Hernández, M. Wilford, H. Rodrı́guez, J. Domı́nguez, M. Cepero, R Castellanos, A. Abdo |
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| Rok vydání: | 2005 |
| Předmět: |
Immunosuppression Therapy
Transplantation medicine.medical_specialty Alcoholic liver disease Cirrhosis business.industry medicine.medical_treatment Cuba Immunosuppression Azathioprine Liver transplantation medicine.disease Hepatitis C Liver Transplantation Surgery Methylprednisolone Liver Cirrhosis Alcoholic medicine Humans business Survival rate Retrospective Studies medicine.drug |
| Zdroj: | Transplantation Proceedings. 37:1505-1506 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2005.02.014 |
| Popis: | From July 4, 1999, when a liver transplantation program was started in Cuba, to October 2003, 66 procedures had been performed in 60 patients. The most frequent reason was cirrhosis caused by hepatitis C virus (29%), and alcoholic cirrhosis (22%). Two patients received simultaneous liver-kidney transplants. Half of the patients were men. Patient ages ranged from 12 to 62 years; the average surgical time was 6 hours; and cold ischemia time was 4 to 14 hours. The average blood consumption was 2033 mL; 2900 mL of plasma and 8 units of platelets were used in 7 cases. Immunosuppression was mainly cyclosporine (Neoral), mycophenolate mofetil or azathioprine, and prednisone. Acute cellular rejections were treated in almost all cases with 3 doses of methylprednisolone. The most frequent complications were biliary (24%), hepatic arterial thrombosis (12%), post-surgical bleeding (10%), acute cellular rejection (24%), and ductopenic rejection (2%). The overall 1-year survival rate was 73.7%. |
| Databáze: | OpenAIRE |
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