Redox basis of exercise physiology
| Autor: | Michalis G. Nikolaidis, Antonios Kyparos, Vassilis Paschalis, Anastasios A. Theodorou, Nikos V. Margaritelis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Bioenergetics Glucose uptake Clinical Biochemistry Biochemistry Redox Article Antioxidants Muscle hypertrophy 03 medical and health sciences 0302 clinical medicine Humans Responses Exercise physiology Muscle Skeletal Redox biology Exercise lcsh:QH301-705.5 chemistry.chemical_classification Reactive oxygen species Adaptations lcsh:R5-920 Organelle Biogenesis Redox homeostasis Organic Chemistry Adaptation Physiological Signaling Cell biology 030104 developmental biology chemistry Mitochondrial biogenesis lcsh:Biology (General) lcsh:Medicine (General) Oxidation-Reduction 030217 neurology & neurosurgery Muscle Contraction |
| Zdroj: | Redox Biology, Vol 35, Iss, Pp 101499-(2020) Redox Biology |
| ISSN: | 2213-2317 |
| Popis: | Redox reactions control fundamental processes of human biology. Therefore, it is safe to assume that the responses and adaptations to exercise are, at least in part, mediated by redox reactions. In this review, we are trying to show that redox reactions are the basis of exercise physiology by outlining the redox signaling pathways that regulate four characteristic acute exercise-induced responses (muscle contractile function, glucose uptake, blood flow and bioenergetics) and four chronic exercise-induced adaptations (mitochondrial biogenesis, muscle hypertrophy, angiogenesis and redox homeostasis). Based on our analysis, we argue that redox regulation should be acknowledged as central to exercise physiology. Graphical abstract Image 1 Highlights • Redox reactions are a fundamental part of human biology. • Exercise responses and adaptations are partially controlled by redox reactions. • Redox signaling should be acknowledged as central to exercise physiology. |
| Databáze: | OpenAIRE |
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