Wheatstone bridge giant-magnetoresistance based cell counter
| Autor: | Chi-Wen Lin, Hao-Ting Huang, Zung-Hang Wei, Chiun-Peng Lee, Mei-Feng Lai |
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| Rok vydání: | 2014 |
| Předmět: |
Wheatstone bridge
Magnetoresistance Biomedical Engineering Biophysics Cell Count Nanotechnology Giant magnetoresistance Biosensing Techniques Cell Separation Cell Line law.invention Magnetics Mice law Cell Line Tumor Electrochemistry Animals Humans Microchannel Magnetic moment Chemistry business.industry Demagnetizing field Equipment Design General Medicine Hydrodynamics Hydrodynamic focusing Optoelectronics business Biosensor Biotechnology |
| Zdroj: | Biosensors and Bioelectronics. 57:48-53 |
| ISSN: | 0956-5663 |
| Popis: | A Wheatstone bridge giant magnetoresistance (GMR) biosensor was proposed here for the detection and counting of magnetic cells. The biosensor was made of a top-pinned spin-valve layer structure, and it was integrated with a microchannel possessing the function of hydrodynamic focusing that allowed the cells to flow in series one by one and ensured the accuracy of detection. Through measuring the magnetoresistance variation caused by the stray field of the magnetic cells that flowed through the microchannel above the GMR biosensor, we can not only detect and count the cells but we can also recognize cells with different magnetic moments. In addition, a magnetic field gradient was applied for the separation of different cells into different channels. |
| Databáze: | OpenAIRE |
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