Haematological and immunological effect of co-administration of extracts of Vernonia amygdalina and Azadirachta indica on normal and diabetic rats
| Autor: | Esien David-Oku, Patrick E. Ebong, M. A. Agiang, Item Justin Atangwho, Eyong U. Eyong |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
biology Red Cell business.industry Vernonia amygdalina Insulin medicine.medical_treatment Cell Azadirachta biology.organism_classification medicine.disease Applied Microbiology and Biotechnology Diabetes haematological and immunological indices Vernonia amygdalina Azadirachta indica medicine.anatomical_structure Endocrinology Internal medicine Diabetes mellitus Genetics medicine business Agronomy and Crop Science Molecular Biology Biotechnology Co administration Diabetic control |
| Zdroj: | African Journal of Biotechnology; Vol 10, No 50 (2011); 10258-10262 Scopus-Elsevier |
| ISSN: | 1684-5315 |
| Popis: | This study evaluated the effect of co-administration of extracts of Vernonia amygdalina Del. (VA) and Azadirachta indica Linn.(AI) on haemapoietic and immunological indices of normal and diabetic rats. White blood cells which were non-significantly decreased (p>0.05) in diabetic control rats relative to the normal control, respectively increased and decreased non-significantly (p>0.05) upon administration of the combined extracts of VA and AI to diabetic and non-diabetic test rats. Packed cell volume, haemoglobin content and red cell count as well as its derived factors (mean cell volume, mean cell haemoglobin and mean cell haemoglobin concentration) of both diabetic and non-diabetic rats were not affected by the treatment, relative to their respective controls. As compared to insulin treatment, the combined extracts significantly increased (p0.05) in diabetic control rats as compared to non-diabetic control was further decreased non-significantly (p>0.05) upon administration of the combined extracts and insulin. Diabetes induction significantly increased CD4+ count (p |
| Databáze: | OpenAIRE |
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