Active Continuous-Flow Micromixer Using an External Braille Pin Actuator Array
| Autor: | Yawar Abbas, Roland Zengerle, Felix von Stetten, Junichi Miwa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Engineering
active micromixer lcsh:Mechanical engineering and machinery Microfluidics Micromixer 02 engineering and technology 01 natural sciences PDMS chip chemistry.chemical_compound Deflection (engineering) Electronic engineering lcsh:TJ1-1570 Electrical and Electronic Engineering continuous-flow chaotic advection channel wall deflection cell sample dilution microfluidic Braille pin actuated platform Microchannel Polydimethylsiloxane business.industry Mechanical Engineering 010401 analytical chemistry 021001 nanoscience & nanotechnology Chip Braille 6. Clean water 0104 chemical sciences chemistry Control and Systems Engineering Optoelectronics 0210 nano-technology Actuator business |
| Zdroj: | Micromachines, Vol 4, Iss 1, Pp 80-89 (2013) Micromachines; Volume 4; Issue 1; Pages: 80-89 |
| Popis: | We present a continuous-flow active micromixer based on channel-wall deflection in a polydimethylsiloxane (PDMS) chip for volume flows in the range up to 2 μL s −1 which is intended as a novel unit operation for the microfluidic Braille pin actuated platform. The chip design comprises a main microchannel connected to a series of side channels with dead ends aligned on the Braille pins. Computer-controlled deflection of the side-channel walls induces chaotic advection in the main-channel, which substantially accelerates mixing in low-Reynolds number flow. Sufficient mixing (mixing index MI below 0.1) of volume flows up to 0.5 μL s −1 could be achieved within residence times ~500 ms in the micromixer. As an application, continuous dilution of a yeast cell sample by a ratio down to 1:10 was successfully demonstrated. The mixer is intended to serve as a component of bio-analytical devices or as a unit operation in the microfluidic Braille pin actuated platform. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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