| Autor: |
Nurdan, Tacyildiz, Hatice Mine, Çakmak, Emel, Ünal, Handan, Dinçaslan, Yasin, Yılmaz, Ömer, Kartal, Gülşah, Tanyıldız, Sonay İncesoy, Özdemir, Gülsan, Yavuz |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of Cancer Research and Therapeutics. 18:712 |
| ISSN: |
0973-1482 |
| DOI: |
10.4103/jcrt.jcrt_80_21 |
| Popis: |
Non-Hodgkin lymphoma (NHL) includes pathologies of different clinical courses, treatments, outcomes. Our study aims to investigate the late effects of NHL survivors (NHLS).Among 59 NHL cases, 50 survivors completed their NHL treatment between 2003 and 2019. Out of 59 patients, the cumulative survival rates and event-free survival rates after 10 years since diagnosis were 82.9% ±5.2% and 84.1% ±5.2%, respectively. In addition, we compared the data related to chronic health and psychosocial conditions with their siblings (n = 61).The age and gender ratios were similar in the NHLS (n = 50) and the control group (n = 61). The rate of nephrotoxicity (P = 0.02) and the frequency of admission to the hospital (P0.01) were significantly higher in the survivors than in the control group. Cardiotoxicity is detected in 3 (6%) of NHLS with cumulative anthracycline dose300 mg/mNephrotoxicity is a statistically more common late effect than the others in the survivors. We observe cardiotoxicity in low cumulative doses of anthracycline. A more significant number of patients is required to reveal late side effects on novel drugs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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