Patient-reported-outcomes in subjects with painful lumbar or cervical radiculopathy treated with pregabalin: evidence from medical practice in primary care settings
| Autor: | Xavier Masramón, Concepción Pérez, Javier Rejas, María T. Saldaña, Ana Navarro |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Immunology Pregabalin Clinical practice Hospital Anxiety and Depression Scale law.invention Randomized controlled trial Rheumatology law medicine Immunology and Allergy Humans Prospective Studies Prospective cohort study Radiculopathy Depression (differential diagnoses) gamma-Aminobutyric Acid Aged Analgesics Evidence-Based Medicine Primary Health Care business.industry Chronic pain Epidemiologic studies Middle Aged medicine.disease Treatment Outcome Outcomes research Physical therapy Anxiety Neuralgia Original Article Female Spondylosis medicine.symptom business medicine.drug Follow-Up Studies |
| Zdroj: | Rheumatology International |
| ISSN: | 1437-160X 0172-8172 |
| Popis: | The objective of this study was to evaluate the effect of pregabalin in painful cervical or lumbosacral radiculopathy treated in Primary Care settings under routine clinical practice. An observational, prospective 12-week secondary analysis was carried-out. Male and female above 18 years, naive to PGB, with refractory chronic pain secondary to cervical/lumbosacral radiculopathy were enrolled. SF-MPQ, Sheehan Disability Inventory, MOS Sleep Scale, Hospital Anxiety and Depression Scale and the EQ-5D were administered. A total of 490 (34%) patients were prescribed PGB-monotherapy, 702 (48%) received PGB add-on, and 159 (11%) were administered non-PGB drugs. After 12 weeks, significant improvements in pain, associated symptoms of anxiety, depression and sleep disturbances, general health; and level of disability were observed in the three groups, being significantly greater in PGB groups. In routine medical practice, monotherapy or add-on pregabalin is associated with substantial pain alleviation and associated symptoms improvements in painful cervical or lumbosacral radiculopathy. |
| Databáze: | OpenAIRE |
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