Cranberry: A Promising Natural Source of Potential Nutraceuticals with Anticancer Activity
| Autor: | Apostolos Zarros, Georgios K. Vasios, Stamatios Theocharis, Constantinos Giaginis, Maria Mantzorou, Eleni Pavlidou |
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| Rok vydání: | 2019 |
| Předmět: |
Cancer Research
Angiogenesis Antioxidants Metastasis 03 medical and health sciences 0302 clinical medicine Nutraceutical In vivo Neoplasms medicine Humans Cell Proliferation 030304 developmental biology Pharmacology 0303 health sciences Cancer prevention Plant Extracts Cell growth business.industry Cancer medicine.disease Antineoplastic Agents Phytogenic In vitro Vaccinium macrocarpon 030220 oncology & carcinogenesis Dietary Supplements Cancer research Molecular Medicine business |
| Zdroj: | Anti-Cancer Agents in Medicinal Chemistry. 19:1672-1686 |
| ISSN: | 1871-5206 |
| DOI: | 10.2174/1871520619666190704163301 |
| Popis: | Studies have shown that cranberry and its components may exert anticancer properties. The present study aims to critically summarise the existing experimental studies evaluating the potential effects of cranberry on cancer prevention and treatment. PubMed database was searched to identify relevant studies. Current in vitro studies have indicated that cranberry and/or its components may act as chemopreventive agents, diminishing the risk for cancer by inhibiting cells oxidation and inflammatory-related processes, while they may also exert chemotherapeutic effects by inhibiting cell proliferation and angiogenesis, inducing cell apoptosis and attenuating the ability of tumour cells to invade and metastasis. Limited in vivo studies have further documented potential anticancer activity. Cranberry could be considered as a conglomeration of potential effective anticancer druglike compounds. |
| Databáze: | OpenAIRE |
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