Eczematous dermatitis in primary immunodeficiencies: A review of cutaneous clues to diagnosis
| Autor: | Suzanne Skoda-Smith, Markus D. Boos, Sidney Hoskins, Troy R. Torgerson |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Cutaneous eruptions business.industry Primary Immunodeficiency Diseases Immunology Eczema medicine.disease Dermatology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Immune system Primary immunodeficiency Humans Immunology and Allergy Medicine Eczematous dermatitis business Immunodeficiency 030215 immunology |
| Zdroj: | Clinical Immunology. 211:108330 |
| ISSN: | 1521-6616 |
| DOI: | 10.1016/j.clim.2019.108330 |
| Popis: | Primary immunodeficiency Disorders (PIDD) are a varied group of heritable disorders characterized by defects in components of the innate and/or adaptive arms of the immune system. Although diagnosing these disorders is often challenging, the skin is a readily accessible and easily assessable organ that may provide clues to a diagnosis of PIDD. Specifically, many immunodeficiencies are associated with characteristic cutaneous eruptions that, based on their morphology, distribution and symptomatology, may suggest a specific underlying diagnosis. This review will discuss an approach to identifying and managing PIDDs that typically present with eczematous dermatitis. |
| Databáze: | OpenAIRE |
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