Sertraline-Induced Acute Eosinophilic Pneumonia
| Autor: | Ademayowa Ademiluyi, James Appiah-Pippim, Prakash Adhikari, Krystal Alexander |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Pulmonology government.form_of_government 030204 cardiovascular system & hematology Allergy/Immunology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Eosinophilic pneumonia Respiratory system Adverse effect Pulmonary Eosinophilia Sertraline sertraline business.industry acute eosinophilic pneumonia General Engineering ssri medicine.disease Discontinuation eosinophilic pneumonia Acute eosinophilic pneumonia Respiratory failure antidepressants government business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.12022 |
| Popis: | Acute eosinophilic pneumonia (AEP) is a rare but severe respiratory syndrome characterized by fever, hypoxemic respiratory failure, diffuse pulmonary infiltrates, and pulmonary eosinophilia. The most common cause of AEP is idiopathic, but it can be associated with antidepressant medications like sertraline. A 76-year-old female presented to our ED with acute hypoxemic respiratory failure. She had no history of smoking or prior lung disease. She did not improve after treatment with broad spectrum antibiotics so a trial of corticosteroids was initiated. Her work-up was negative for infectious or collagen vascular causes of the respiratory failure. She was diagnosed with AEP associated with sertraline. Her condition improved with corticosteroid therapy after discontinuation of sertraline. This case report highlights AEP as a possible adverse reaction of sertraline. Prompt discontinuation of the offending drug is necessary for early recovery. |
| Databáze: | OpenAIRE |
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