Six-Month Outcomes in Patients Hospitalized with Severe COVID-19

Autor: Emily Duan, Leora I. Horwitz, Kira Garry, Himali Weerahandi, Felicia Mendoza, Tamara Kahan, Sneha Sharma, Alexander M Prete, Hannah C. Karpel, Katherine Hochman
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of General Internal Medicine
ISSN: 1525-1497
0884-8734
Popis: Background Previous work has demonstrated that patients experience functional decline at 1–3 months post-discharge after COVID-19 hospitalization. Objective To determine whether symptoms persist further or improve over time, we followed patients discharged after hospitalization for severe COVID-19 to characterize their overall health status and their physical and mental health at 6 months post-hospital discharge. Design Prospective observational cohort study. Participants Patients ≥ 18 years hospitalized for COVID-19 at a single health system, who required at minimum 6 l of supplemental oxygen during admission, had intact baseline functional status, and were discharged alive. Main Measures Overall health status, physical health, mental health, and dyspnea were assessed with validated surveys: the PROMIS® Global Health-10 and PROMIS® Dyspnea Characteristics instruments. Key Results Of 152 patients who completed the 1 month post-discharge survey, 126 (83%) completed the 6-month survey. Median age of 6-month respondents was 62; 40% were female. Ninety-three (74%) patients reported that their health had not returned to baseline at 6 months, and endorsed a mean of 7.1 symptoms. Participants’ summary t-scores in both the physical health and mental health domains at 6 months (45.2, standard deviation [SD] 9.8; 47.4, SD 9.8, respectively) remained lower than their baseline (physical health 53.7, SD 9.4; mental health 54.2, SD 8.0; p
Databáze: OpenAIRE
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