Histamine Blood Concentration in Ischemic Heart Disease Patients
| Autor: | Aleksandra Tomic-Lucic, Zdravko Obradovic, Nemanja Zdravkovic, Gvozden Rosic, Vladimir Zdravkovic, Suzana Pantovic, Maja Colic, Mirko Rosic |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Acute coronary syndrome Myocardial ischemia Article Subject lcsh:Biotechnology Health Toxicology and Mutagenesis Myocardial Ischemia lcsh:Medicine Coronary Artery Disease Disease Coronary artery disease chemistry.chemical_compound Blood concentration lcsh:TP248.13-248.65 Internal medicine Troponin I Genetics Humans Medicine Acute Coronary Syndrome Molecular Biology Aged business.industry lcsh:R General Medicine Middle Aged medicine.disease Coronary Occlusion chemistry Coronary occlusion Cardiology Molecular Medicine Female business Histamine Research Article Biotechnology |
| Zdroj: | Journal of Biomedicine and Biotechnology, Vol 2011 (2011) Journal of Biomedicine and Biotechnology |
| ISSN: | 1110-7251 1110-7243 |
| Popis: | The aim of this study was to investigate histamine blood concentration in subjects suffering from different types of ischemic heart diseases during the period of eight days. Our results showed that the histamine blood level was associated with different types of ischemic heart diseases. The blood histamine level in all investigated patients was significantly higher when compared to control subjects (44.87 ± 1.09 ng mL−1), indicating the increase of histamine release in patients suffering from coronary diseases. In patients suffering from ACS-UA and ACS-STEMI, the second day peak of histamine level occurs (90.85 ± 6.34 ng mL−1and 121.7 ± 6.34 ng mL−1, resp.) probably as the reperfusion event. Furthermore, our data suggest that histamine can be additional parameter of myocardial ischemia along with cardiac specific enzymes and may prove to be an excellent single prognostic marker for multitude of ischemic heart diseases. |
| Databáze: | OpenAIRE |
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