Amyotrophic lateral sclerosis and ocular flutter
Autor: | Michelle S Balaratnam, R J Guiloff, Adolfo M. Bronstein, Barry M. Seemungal, Guy D. Leschziner |
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Rok vydání: | 2010 |
Předmět: |
Adult
Male Ataxia genetic structures Fixation Ocular Nystagmus Inhibitory postsynaptic potential Nystagmus Pathologic Ocular flutter Biological Clocks Humans Medicine Amyotrophic lateral sclerosis business.industry musculoskeletal neural and ocular physiology Amyotrophic Lateral Sclerosis fungi General Medicine medicine.disease nervous system Neurology Disinhibition Fixation (visual) Neurology (clinical) Brainstem medicine.symptom business Neuroscience |
Zdroj: | Amyotrophic Lateral Sclerosis. 11:331-334 |
ISSN: | 1471-180X 1748-2968 |
DOI: | 10.3109/17482960902875133 |
Popis: | A previously unreported association of amyotrophic lateral sclerosis and ocular flutter is presented. It is hypothesized that initial loss of brainstem inhibitory interneurons resulted in disinhibition of burst interneurons and that the ocular flutter subsequently disappeared as burst interneurons also became affected by the disease process. The association adds clinical evidence of involvement of brainstem interneurons to other evidence of involvement of neurons other than motor neurons in the disease process. |
Databáze: | OpenAIRE |
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