Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study

Autor: Maryam Bahrani, Soheila Abolghasemi, Hesam Adin Atashi, Shahla Abolghasemi, Aida Rezaei Nejad, Giti Dehghan Manshadi, Hamid Zaferani Arani, Homayoon Khaledian, Atefe Kazemzade Bejandi, Pantea Bozorg Savodji, Seyyed Mojtaba Ghorani, Mohammad Hoseinian
Rok vydání: 2021
Předmět:
Male
RNA viruses
Viral Diseases
Pediatrics
Coronaviruses
Physiology
Fevers
Iran
Logistic regression
medicine.disease_cause
Betamethasone
Severity of Illness Index
Body Mass Index
Geographical Locations
Medical Conditions
Epidemiology
Pandemic
Medicine and Health Sciences
Coughing
Medicine
Pathology and laboratory medicine
Coronavirus
Multidisciplinary
Mortality rate
Incidence (epidemiology)
Immunoglobulins
Intravenous
Middle Aged
Medical microbiology
Chemistry
Infectious Diseases
Physical Sciences
Viruses
Female
SARS CoV 2
Pathogens
Research Article
Chemical Elements
Adult
medicine.medical_specialty
Asia
Fever
SARS coronavirus
Death Rates
Science
macromolecular substances
Microbiology
Signs and Symptoms
Population Metrics
Severity of illness
Humans
Pandemics
Aged
Retrospective Studies
SARS
Population Biology
SARS-CoV-2
business.industry
Organisms
Viral pathogens
COVID-19
Biology and Life Sciences
Covid 19
Retrospective cohort study
COVID-19 Drug Treatment
Microbial pathogens
Oxygen
Logistic Models
Cough
People and Places
Clinical Medicine
Physiological Processes
business
Zdroj: PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0246314 (2021)
ISSN: 1932-6203
Popis: During the last months of the coronavirus pandemic, with all those public restrictions and health interventions, the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears now to have been raised in some countries around the world. Iran was one of those first countries facing the second wave of coronavirus, due to the lack of appropriate public restrictions because of economic problems the country is facing. The clinical and demographic characteristics of severe cases and non-severe cases of Coronavirus Disease (COVID-19) in 192 patients in Tehran, Iran, between June 16 and July 11, 2020, were investigated. The patients were divided into severe cases (n = 82) and non-severe cases (n = 110). Demographic and clinical characteristics were compared between the two study clusters. The mean age was 54.6 ± 17.2 years, and the most common presenting symptom was persistent cough (81.8%) and fever (79.7%). The logistic regression model revealed that age, BMI, and affected family members were statistically associated with severity. Patients with complicated conditions of disorders faced more hospitalization days and medical care than the average statistical data. As the coronavirus spike in the case and death reports from June 2020, we observed the rise in the incidence of severe cases, where 42.7% (82/192) of cases have resulted in severe conditions. Our findings also suggested that the effect of IFB (Betamethasone) was more valid than the other alternative drugs such as LPV/r and IVIg.
Databáze: OpenAIRE
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