Prevalence of Mixed Connective Tissue Disease in a Population-Based Registry of American Indian/Alaska Native People in 2007
| Autor: | Janet M. Johnston, Caroline Gordon, S. Sam Lim, Elizabeth D. Ferucci, Charles G. Helmick |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Adolescent Population 03 medical and health sciences Young Adult 0302 clinical medicine Mixed connective tissue disease Rheumatology Epidemiology medicine Prevalence Humans 030212 general & internal medicine Registries education Aged Mixed Connective Tissue Disease Retrospective Studies 030203 arthritis & rheumatology education.field_of_study business.industry Medical record Middle Aged medicine.disease Alaskan Natives Connective tissue disease Confidence interval Population Surveillance Indians North American Female Diagnosis code business Population-Based Registry Demography Follow-Up Studies |
| Zdroj: | Arthritis careresearch. 69(8) |
| ISSN: | 2151-4658 |
| Popis: | Objective: The objective of this surveillance project was to determine the prevalence of mixed connective tissue disease (MCTD) in 2007 in the Indian Health Service (IHS) active clinical population from 3 regions of the United States. Methods: The IHS Lupus Registry was designed to identify possible MCTD cases in addition to lupus. The population denominator for this report includes American Indian or Alaska Native adults within the IHS active clinical population in 2007, residing in select communities in 3 regions of the US. Potential MCTD cases were identified using a broad range of diagnostic codes and were confirmed by detailed medical record abstraction. Classification as MCTD for this analysis required both rheumatologist diagnosis of MCTD without diagnosis of other connective tissue disease and documentation of the Alarcon-Segovia criteria in the medical record. Prevalence was also calculated using two alternate definitions of MCTD. Results: The age-adjusted prevalence of MCTD using our primary definition was 6.4 per 100,000 (95% confidence interval (CI) 2.8-12.8). The prevalence was higher in women than men using all three definitions of MCTD, and no men met the primary definition of MCTD. Conclusion: The first population-based estimates of the prevalence of MCTD in the US American Indian/Alaska Native population show that the prevalence appears to be higher than in other populations. Additional population-based estimates are needed to better understand the epidemiology of MCTD. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text