Is there a safe plateau pressure in ARDS? The right heart only knows

Autor: François Jardin, Antoine Vieillard-Baron
Rok vydání: 2007
Předmět:
Zdroj: Intensive Care Medicine. 33:444-447
ISSN: 1432-1238
0342-4642
Popis: Airway pressure limitation is now a largely accepted strategy in adult respiratory distress syndrome (ARDS) patients; however, some debate persists about the exact level of plateau pressure which can be safely used. The objective of the present study was to examine if the echocardiographic evaluation of right ventricular function performed in ARDS may help to answer to this question. For more than 20 years, we have regularly monitored right ventricular function by echocardiography in ARDS patients, during two different periods, a first (1980–1992) where airway pressure was not limited, and a second (1993–2006) where airway pressure was limited. By pooling our data, we can observe the effect of a large range of plateau pressure upon mortality rate and incidence of acute cor pulmonale. In this whole group of 352 ARDS patients, mortality rate and incidence of cor pulmonale were 80 and 56%, respectively, when plateau pressure was > 35 cmH2O; 42 and 32%, respectively, when plateau pressure was between 27 and 35 cmH2O; and 30 and 13%, respectively, when plateau pressure was
Databáze: OpenAIRE