Mechanisms of PhotoBioModulation (PBM) focused on oral mucositis prevention and treatment: a scoping review
| Autor: | Safa Louati, Wafa Bouleftour, René-Jean Bensadoun, Nicolas Magné, Jean-Baptiste Guy, Claire Rodriguez-Lafrasse, Elodie A. Courtois |
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| Přispěvatelé: | NeoMedLight, Institut de Cancérologie Lucien Neuwirth, CHU Saint-Etienne, Centre de Haute Énergie, Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2020 |
| Předmět: |
Oncology
medicine.medical_specialty [SDV.CAN]Life Sciences [q-bio]/Cancer chemical and pharmacologic phenomena Oral mucositis 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Laser therapy Internal medicine Neoplasms Mucositis Medicine Malignant cells Humans Prospective Studies Low-Level Light Therapy Prospective cohort study General Dentistry Severe complication Stomatitis business.industry Prevention fungi Cancer RK1-715 Chemoradiotherapy Phototherapy Photobiomodulation medicine.disease 3. Good health 030220 oncology & carcinogenesis Dentistry Cancer cell business Research Article |
| Zdroj: | BMC Oral Health BMC Oral Health, Vol 21, Iss 1, Pp 1-11 (2021) BMC Oral Health, BioMed Central, 2021, 21 (1), ⟨10.1186/s12903-021-01574-4⟩ |
| ISSN: | 1472-6831 |
| Popis: | Background Oral mucositis (OM) is a severe complication cancer patients undergo when treated with chemoradiotherapy. Photobiomodulation (PBM) therapy also known as low-level laser therapy has been increasingly used for the treatment of such oral toxicity. The aim of this review is to discuss the mechanisms of photobiomodulation (PBM) regarding OM prevention and treatment, and more precisely to focus on the effect of PBM on tumor and healthy cells. Methods MEDLINE/PubMed, and google scholar were searched electronically. Selected studies were focusing on PBM effects on tumor and healthy cells. Results PBM interactions with the tissue and additional mechanism in OM therapy were detailed in this review. Moreover, this review highlighted a controversy about the carcinogenic effect of PBM. Indeed, Many studies reported that PBM could enhance malignant cell proliferation; suggesting that PBM would have no protective effect. In addition to acting on cancer cells, PBM may damage healthy cells. Conclusion More prospective studies are needed to assess the effect of PBM on cancer cells in order to improve its use for OM prevention and treatment. |
| Databáze: | OpenAIRE |
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