Graves’ Thyrotoxicosis Following SARS-CoV-2 Infection
| Autor: | Mazen Al Mushref, Asaf Harris |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Graves' disease coronavirus Case Report 030209 endocrinology & metabolism Disease SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Diseases of the endocrine glands. Clinical endocrinology thyroid 03 medical and health sciences 0302 clinical medicine Thyroid-stimulating hormone T4 thyroxine Genetic predisposition Palpitations Medicine COVID-19 coronavirus disease 2019 SARS-CoV-2 business.industry Thyroid COVID-19 General Medicine Environmental exposure GD Graves’ disease RC648-665 medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis ED emergency department Thyroid function medicine.symptom Graves’ disease business TSH thyroid-stimulating hormone |
| Zdroj: | AACE Clinical Case Reports, Vol 7, Iss 1, Pp 14-16 (2021) AACE Clinical Case Reports |
| ISSN: | 2376-0605 |
| DOI: | 10.1016/j.aace.2020.12.005 |
| Popis: | Objective: Graves’ disease is an autoimmune thyroid disease that is thought to develop following environmental exposure in patients with genetic predisposition. Our objective is to present the first report of Graves’ disease onset immediately following recovery from mild coronavirus disease 2019 (COVID-19), a close temporal occurrence that should be studied further. Methods: We describe the clinical course and laboratory features, including thyroid function studies, antibody testing, and polymerase chain reaction testing for severe acute respiratory syndrome coronavirus 2. Results: A 21-year-old woman with prediabetes, obesity, asthma, and gastroesophageal reflux disease presented to the emergency department reporting 3 days of tachycardia, palpitations, anxiety, and shortness of breath. Laboratory investigation revealed a thyroid-stimulating hormone level of 0.01 (0.30-5.00) mcIU/mL with a free thyroxine level of 3.8 (0.6-1.6) ng/dL, prompting endocrinology consultation. On physical examination, she had mild diffuse thyromegaly without tenderness and a history, which included hypothyroidism in her mother. Antibody testing results demonstrated thyroid-stimulating immunoglobulin and thyrotropin receptor antibody levels of 2.6 ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|