Estimating Mental Health Conditions of Patients with Opioid Use Disorder
| Autor: | Ibrahim M. Shokry, Rui Tao, Christopher Minnerly, Steven L. Bressler |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
medicine.diagnostic_test Article Subject business.industry Opioid use disorder Context (language use) Electroencephalography medicine.disease Mental health 03 medical and health sciences EEG microstates 0302 clinical medicine medicine.anatomical_structure Scalp Neuroplasticity medicine lcsh:H1-99 lcsh:Social sciences (General) Eeg electrodes business Neuroscience 030217 neurology & neurosurgery 030304 developmental biology Research Article |
| Zdroj: | Journal of Addiction Journal of Addiction, Vol 2019 (2019) |
| ISSN: | 2090-7834 |
| DOI: | 10.1155/2019/8586153 |
| Popis: | Objectives. Noninvasive estimation of cortical activity aberrance may be a challenge but gives valuable clues of mental health in patients. The goal of the present study was to characterize specificity of electroencephalogram (EEG) electrodes used to assess spectral powers associated with mental health conditions of patients with opioid use disorder. Methods. This retrospective study included 16 patients who had been diagnosed with opioid use disorder in comparison with 16 sex- and age-matched healthy controls. EEG electrodes were placed in the frontal (FP1, FP2, F3, F4, F7, F8, and Fz), central (C3, C4, and Cz), temporal (T3, T4, T5, and T6), parietal (P3, P4, and Pz), and occipital scalp (O1 and O2). Spectral powers of δ, θ, α, β, and γ oscillations were determined, and their distribution was topographically mapped with those electrodes on the scalp. Results. Compared to healthy controls, the spectral powers at low frequencies (δ and θ) were increased in most electrodes across the scalp, while powers at the high frequencies (>12 Hz; β and γ) were selectively increased only at electrodes located in the frontal and central scalp. Among 19 electrodes, F3, F4, Fz, and Cz were highly specific in detecting increases in δ, θ, β, and γ powers of patients with opioid use disorders. Conclusion. Results of the present study demonstrate that spectral powers are topographically distributed across the scalp, which can be quantitatively characterized. Electrodes located at F3, F4, Fz, and Cz could be specifically utilized to assess mental health in patients with opioid use disorders. Mechanisms responsible for neuroplasticity involving cortical pyramidal neurons and μ-opioid receptor regulations are discussed within the context of changes in EEG microstates. |
| Databáze: | OpenAIRE |
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