Determination of Constant Rates of Adsorption of Ligand on DNA: Analysis of Correlation Functions
| Autor: | Yu. Babayan, V.B. Arakelyan, G. Potikyan |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Quantitative Biology::Biomolecules
Ligand Chemistry Kinetics Analytical chemistry DNA General Medicine Models Theoretical Ligands Decomposition Quantitative Biology::Subcellular Processes Correlation function (statistical mechanics) Adsorption Models Chemical Structural Biology Molecule Physical chemistry Constant (mathematics) Molecular Biology Protein Binding Macromolecule |
| Zdroj: | Journal of Biomolecular Structure and Dynamics. 18:231-235 |
| ISSN: | 1538-0254 0739-1102 |
| Popis: | Correlation functions and spectral density of the number of molecules of ligand bound to DNA are calculated theoretically. Kinetics of rates of formation and decomposition of the complex are determined by calculating the dependence of correlation function on concentration of ligand in solution. The analysis of spectral density allows to distinguish “fast” and “slow” adsorption of ligands on macromolecule. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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