Antifungal sesquiterpene from the root of Vernonanthura tweedieana
| Autor: | Aida Portillo, Roser Vila, Teodor Parella, Blanca Freixa, Joseph Casanova, Esteban Ferro, Salvador Cañigueral |
|---|---|
| Přispěvatelé: | Sciences pour l'environnement (SPE), Centre National de la Recherche Scientifique (CNRS)-Université Pascal Paoli (UPP), Lugrezi, Cathy |
| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
food.ingredient
[CHIM.ANAL] Chemical Sciences/Analytical chemistry Antifungal Agents Fractionation Microbial Sensitivity Tests Biology Pharmacognosy Sesquiterpene 01 natural sciences Plant Roots 03 medical and health sciences chemistry.chemical_compound food [CHIM.ANAL]Chemical Sciences/Analytical chemistry Drug Discovery Botany Trichophyton ComputingMilieux_MISCELLANEOUS Dichloromethane Pharmacology 0303 health sciences Traditional medicine 030306 microbiology Plant Extracts Asteraceae biology.organism_classification Vernonanthura 0104 chemical sciences Fungicide 010404 medicinal & biomolecular chemistry chemistry Sesquiterpenes Vernonia |
| Zdroj: | Journal of Ethnopharmacology Journal of Ethnopharmacology, Elsevier, 2005, 97, pp.49-52 |
| ISSN: | 0378-8741 |
| Popis: | The bioassay-guided fractionation of the antifungal dichloromethane extract from the roots of Vernonanthura tweedieana (Baker) H. Rob. (Asteraceae), using an agar overlay bioautographic method, allowed the isolation of one active sesquiterpene (1), identified as 6-cinnamoyloxy-1-hydroxyeudesm-4-en-3-one. Minimal inhibitory concentrations (MIC) and minimal fungicidal concentrations (MFC) of 1 showed Trichophyton mentagrophytes as the most sensitive strain, with the same MIC and MFC values (4 microg/ml). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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