Huntington's Disease and Employment: The Relative Contributions of Cognitive and Motor Decline to the Decision to Leave Work
Autor: | Karen E. Anderson, Rosemary K. Sokas, Jennifer L. Purks, Kristen Watkins, Hope Heller, Anagha Kumar |
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Rok vydání: | 2018 |
Předmět: |
Adult
Employment Male medicine.medical_specialty Decision Making Disease Behavioral Symptoms Audiology 050105 experimental psychology 03 medical and health sciences Cellular and Molecular Neuroscience Disability Evaluation Young Adult 0302 clinical medicine Huntington's disease Chorea Medicine Humans 0501 psychology and cognitive sciences Cognitive Dysfunction Cognitive decline Age of Onset Association (psychology) Retirement business.industry 05 social sciences Cognition Middle Aged medicine.disease Huntington Disease Workforce Disease Progression Linear Models Observational study Female Neurology (clinical) business 030217 neurology & neurosurgery Stroop effect |
Zdroj: | Journal of Huntington's disease. 7(4) |
ISSN: | 1879-6400 |
Popis: | BACKGROUND Huntington's disease (HD) presents with motor, cognitive, and behavioral symptoms that impair functional capacity and the ability to maintain employment. The relative contribution of cognitive decline to work disability remains controversial. OBJECTIVE To evaluate the association of cognitive decline, compared with motor decline, with the decision to leave work. METHODS Data from the Enroll-HD observational study were analyzed. The correlation of age of cognitive symptom onset and age of motor symptom onset with age at leaving work was assessed. The association of the Stroop Color Naming Test (SCNT) cognitive assessment and the Total Motor Score (TMS) assessment (reverse scored) with the Total Functional Capacity (TFC) assessment was also assessed. RESULTS For every year delay in cognitive symptom onset, there was a 0.806 year increase in age at leaving work (SE = 0.030, p |
Databáze: | OpenAIRE |
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