Huntington's Disease and Employment: The Relative Contributions of Cognitive and Motor Decline to the Decision to Leave Work

Autor: Karen E. Anderson, Rosemary K. Sokas, Jennifer L. Purks, Kristen Watkins, Hope Heller, Anagha Kumar
Rok vydání: 2018
Předmět:
Zdroj: Journal of Huntington's disease. 7(4)
ISSN: 1879-6400
Popis: BACKGROUND Huntington's disease (HD) presents with motor, cognitive, and behavioral symptoms that impair functional capacity and the ability to maintain employment. The relative contribution of cognitive decline to work disability remains controversial. OBJECTIVE To evaluate the association of cognitive decline, compared with motor decline, with the decision to leave work. METHODS Data from the Enroll-HD observational study were analyzed. The correlation of age of cognitive symptom onset and age of motor symptom onset with age at leaving work was assessed. The association of the Stroop Color Naming Test (SCNT) cognitive assessment and the Total Motor Score (TMS) assessment (reverse scored) with the Total Functional Capacity (TFC) assessment was also assessed. RESULTS For every year delay in cognitive symptom onset, there was a 0.806 year increase in age at leaving work (SE = 0.030, p
Databáze: OpenAIRE
Nepřihlášeným uživatelům se plný text nezobrazuje