Recurrent Spontaneous Arterial Dissections
| Autor: | James D. Kuiper, Bahram Mokri, Wouter I. Schievink, David G. Piepgras |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Adolescent Cervical Artery Vertebral artery Recurrence Risk Factors medicine.artery medicine Humans Family Family history Risk factor Aged Retrospective Studies Advanced and Specialized Nursing Arterial dissection Vascular disease business.industry Intracranial Aneurysm Middle Aged medicine.disease Cerebral Angiography Surgery Aortic Dissection Dissection Relative risk Female Neurology (clinical) Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | Stroke. 27:622-624 |
| ISSN: | 1524-4628 0039-2499 |
| DOI: | 10.1161/01.str.27.4.622 |
| Popis: | Background and Purpose Among patients with spontaneous cervical artery dissections, the risk of recurrent arterial dissection is relatively low at 1% per year, but this risk may be higher for patients with a family history of arterial dissections. We compared the risk of a recurrent arterial dissection in patients with familial versus nonfamilial disease. Methods Long-term follow-up was established in 200 patients (104 women and 96 men with a mean age of 44.9 years) with spontaneous cervical artery dissections evaluated at a single institution between 1970 and 1990. Results Among the 200 patients, 10 (5%) were identified who had a family history of spontaneous arterial dissections. In a multivariate analysis, family history was the only significant variable associated with the risk of recurrent dissection (χ 2 =15.51; P =.0001). A recurrent arterial dissection was identified in 5 (50%) of the 10 patients with familial disease compared with 11 (5.8%) of the 190 patients with nonfamilial disease, with an estimated relative risk of 6.3 (95% confidence interval, 2.2 to 18.3; P =.0007). Conclusions Among patients with spontaneous cervical artery dissections, a family history of arterial dissection is an important risk factor for the development of a recurrent arterial dissection. |
| Databáze: | OpenAIRE |
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