Increased levels of circulating IL-10 in persons recovered from hepatitis C virus (HCV) infection compared with persons with active HCV infection
| Autor: | Richard Phillips, Michael Owusu, Margaret T. Frempong, Fred Stephen Sarfo, Dorcas Owusu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_treatment Hepatitis C virus lcsh:Medicine Aspartate transaminase medicine.disease_cause General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Liver disease 0302 clinical medicine Medicine Humans Prospective Studies lcsh:Science (General) Prospective cohort study lcsh:QH301-705.5 Cytokine Spontaneous recovery biology business.industry lcsh:R General Medicine Hepatitis C Hepatitis C Chronic medicine.disease digestive system diseases Interleukin-10 Interleukin 10 Research Note 030104 developmental biology lcsh:Biology (General) Alanine transaminase Immunology biology.protein 030211 gastroenterology & hepatology business lcsh:Q1-390 |
| Zdroj: | BMC Research Notes BMC Research Notes, Vol 13, Iss 1, Pp 1-7 (2020) |
| ISSN: | 1756-0500 |
| Popis: | Objective Approximately 70% of all hepatitis C (HCV) infections develop chronic disease. Active or exacerbated chronic hepatitis C infection subsequently progress to liver disease. The role of T-cells secretions in achieving viral clearance is still not well understood. Thus, the current study was set to determine the relationship between the T cell cytokine profiles, biochemical parameters and persistent HCV infection or spontaneous recovery. Results Twenty-five percent (41/163) of the anti-HCV positive participants had recovered from HCV and had significantly higher concentration of IL-10 compared to those with active HCV infection (P |
| Databáze: | OpenAIRE |
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