A new gastric impedancemeter for detecting the development of a visceral edema: a proof-of-concept study on an experimental endotoxemic shock
| Autor: | Pierre-Yves Gumery, Pascal Defaye, J.J. Thiebault, Skandar Basrour, Philippe Cinquin, François Boucher, J. Hermet, D. Remond, Cindy Dopierala, M.R. Frikha, A. Carabelli, S. Junot, Patrick Tuvignon, B. Cohade |
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| Přispěvatelé: | Physiologie cardio-Respiratoire Expérimentale Théorique et Appliquée (TIMC-IMAG-PRETA), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Techniques pour l'Evaluation et la Modélisation des Actions de la Santé (TIMC-IMAG-ThEMAS), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS), Agressions Pulmonaires et Circulatoires dans le Sepsis - UR (APCSé), Unité de Nutrition Humaine (UNH), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Circuits, Devices and System Integration (CDSI), Techniques de l'Informatique et de la Microélectronique pour l'Architecture des systèmes intégrés (TIMA), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Systèmes Nanobiotechnologiques et Biomimétiques (TIMC-IMAG-SyNaBi), ANR-19-P3IA-0003,MIAI,MIAI @ Grenoble Alpes(2019), Circuits, Devices and System Integration (TIMA-CDSI) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Acute decompensated heart failure Swine [SDV]Life Sciences [q-bio] 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine Submucosa Edema medicine Animals Visceral Edema ComputingMilieux_MISCELLANEOUS Heart Failure Tissue water business.industry Stomach digestive oral and skin physiology Shock medicine.disease Endotoxemia medicine.anatomical_structure Heart failure Shock (circulatory) Cardiology [SDV.IB]Life Sciences [q-bio]/Bioengineering medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | 42. Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC) 42. Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC), Jul 2020, Montreal, Canada. pp.4433-4436, ⟨10.1109/EMBC44109.2020.9175897⟩ EMBC 2020 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medical and Biological Engineering Society 2020 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medical and Biological Engineering Society, Jul 2020, Montreal, Canada. pp.4433-4436, ⟨10.1109/EMBC44109.2020.9175897⟩ |
| DOI: | 10.1109/EMBC44109.2020.9175897⟩ |
| Popis: | International audience; Visceral congestion and edema are important features of advanced heart failure. Monitoring the evolution of fluid content in the gastric wall might provide an index of the development of this phenomenon and therefore constitute an innovative marker to early detect acute decompensated heart failure episodes. The evolution of the fluid content in the gastric wall is measured using a device implanted in the submucosa layer of the fundic region of the stomach. The device composed of two electrodes measures the bioimpedance values that reflects the water content of the tissue.An in-vivo experiment in a pig was carried out to validate the feasibility of detecting the gastric bioimpedance variations during the development of an experimental acute visceral edema caused by an endotoxemic shock. Our preliminary results confirm the possibility to monitor the bioimpedance variations due to moderate changes in tissue water content (10%) with a two-electrode configuration device implanted in the submucosa of the stomach. |
| Databáze: | OpenAIRE |
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