Clinical profile and mortality predictors for tuberculosis disease among patients with solid tumours

Autor:	Camila Agra Gomes de Lira, Driele Peixoto Bittencourt, Camila da Silva Bicalho, Patrícia Bonazzi Rodrigues, Maristela Pinheiro Freire, Edson Abdala, Lígia Camera Pierrotti
Rok vydání:	2022
Předmět:	Male Microbiology (medical) Lung Neoplasms Infectious Diseases General Immunology and Microbiology Latent Tuberculosis Humans Mass Screening Tuberculosis Mycobacterium tuberculosis General Medicine
Zdroj:	Infectious Diseases. 54:804-809
ISSN:	2374-4243 2374-4235
Popis:	The characteristics ofWe reviewed the medical records of 126 patients with solid tumours malignancy and who developed TB disease between January 2009 and April 2018 at a cancer referral centre.The most common locations of malignancy were head and neck, with squamous cell carcinoma being the most frequent histological type, the majority (97/126) presenting locally invasive tumours (T3 or T4). A total of 120 had TB pulmonary and the microbiological diagnosis was performed in 103/126. The following variables were associated with the risk of death from TB: DPOC lung cancer, BMI, malnutrition, metastasis and ECOG 3 or 4. Previous chemotherapy treatment was a protective factor.Male, usage of alcohol and smoking were the most predominant patients characteristics in our sample. In the multivariate analysis, lung cancer, presence of metastasis and ECOG ≥ 3 were associated with death from TB.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80641305bd62f4d7156cc9833a5f7842 https://doi.org/10.1080/23744235.2022.2101690 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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