Influence of neurotransplantation on rats' behavior with different conditions of reinforcement
| Autor: | N. G. Mikhailova, I.V. Ermakova, A. V. Zukhar, E.V. Loseva |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
Central nervous system Hypothalamus Experimental and Cognitive Psychology Amygdala Hippocampus Behavioral Neuroscience Fetal Tissue Transplantation Pregnancy Internal medicine medicine Hippocampus (mythology) Animals Brain Tissue Transplantation Reinforcement High probability Cerebral Cortex Neocortex Behavior Animal Quinine Rats Transplantation Endocrinology medicine.anatomical_structure nervous system Conditioning Operant Female Psychology Neuroscience Reinforcement Psychology |
| Zdroj: | Physiologybehavior. 50(6) |
| ISSN: | 0031-9384 |
| Popis: | Recently, we have reported a marked rat lateralization in the T-maze choice. Embryonic rat tissue from neocortex, hippocampus, hypothalamus and amygdala was transplanted into intact rat brains in various combinations: 1) neocortex and hypothalamus (Neo + Hyp); 2) hippocampus and amygdala (Hipp + Amyg); 3) neocortex and hippocampus (Neo + Hipp); and 4) hypothalamus and amygdala (Hyp + Amyg). Once under conditions in which reinforcement was equally qualitative and equally probable, rats in all groups chose the T-maze arm contralateral to the side of implantation. In a second set of experiments, rats were presented a choice between quality and probability of reinforcement. The right arm of the T-maze contained a cup of water 33% of the time (high-quality but low-probability reinforcement). The left sleeve contained a solution of 0.15% quinine in water 100% of the time (low quality but high probability of reinforcement). Rats that received Neo + Hyp transplants chose the T-maze arm that always contained a drink cup with water significantly more often than they chose the arm that always contained the drink cup with quinine solution. Rats that received Hipp + Amyg transplants chose the arm containing the drink cup with quinine solution much more often than the arm that sometimes contained a cup of water. Rats with transplanted Neo + Hyp generally were more active than rats with transplanted Hipp + Amyg. These data suggest that the behavior of rats can be affected by selective transplantation of different brain tissue. |
| Databáze: | OpenAIRE |
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