Life-threatening bacteraemia in HIV-1 seropositive adults admitted to hospital in Nairobi, Kenya
| Autor: | C.F. Gilks, R.J. Brindle, R.S. Newnham, W.M. Watkins, P.G. Waiyaki, J.B.O. Were, L.S. Otieno, P.M. Simani, S.M. Bhatt, G.N. Lule, G.B.A. Okelo, D.A. Warrell |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Salmonella Cross-sectional study Sepsis mortality Human immunodeficiency virus (HIV) medicine.disease_cause Enterobacteriaceae Sepsis Internal medicine Streptococcus pneumoniae Prevalence medicine Humans Acquired Immunodeficiency Syndrome business.industry virus diseases General Medicine Prognosis medicine.disease Kenya Cross-Sectional Studies Bacteremia Immunology HIV-1 Female Viral disease Complication business |
| Zdroj: | The Lancet. 336:545-549 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/0140-6736(90)92096-z |
| Popis: | During 6 months, 506 consecutive adult emergency admissions to hospital in Nairobi were enrolled in a study of bacteraemia and HIV infection. 19% were HIV-1 antibody positive. Significantly more HIV-seropositive than seronegative patients had bacteraemia (26% vs 6%). The predominant organisms isolated from the seropositive patients were Salmonella typhimurium and Streptococcus pneumoniae. Mortality was higher in the seropositive than in the seronegative bacteraemic patients. The findings suggest that non-opportunistic bacteria are important causes of morbidity and mortality in HIV-infected individuals in Africa. |
| Databáze: | OpenAIRE |
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